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Summaries of Newsworthy Clinical Trial Results

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Lung Cancer Trial Results
1.  Annual Report to the Nation Finds Declines in Cancer Incidence and Death Rates; Special Feature Reveals Wide Variations in Lung Cancer Trends across States
(Posted: 11/25/2008) - A new report from the nation's leading cancer organizations shows that, for the first time since the report was first issued in 1998, both incidence and death rates for all cancers combined are decreasing for both men and women, driven largely by declines in some of the most common types of cancer. The report notes that, although the decreases in overall cancer incidence and death rates are encouraging, large state and regional differences in lung cancer trends among women underscore the need to strengthen many state tobacco control programs.

2.  No Survival Benefit from Adjuvant Chemo in Stage 1B NSCLC
(Posted: 10/30/2008) - The paclitaxel-plus-carboplatin adjuvant chemotherapy regimen offers no survival benefit to patients with stage 1B non-small-cell lung cancer, according to a report published online September 22, 2008, in the Journal of Clinical Oncology.

3.  Cetuximab Plus Chemotherapy Extends Survival for Advanced Lung Cancer
(Posted: 06/19/2008) - Patients with advanced non-small-cell lung cancer who received cetuximab (Erbitux) plus chemotherapy lived on average five weeks longer than patients who received chemotherapy alone, according to findings presented at the 2008 ASCO meeting in Chicago.

4.  Radiotherapy Can Prevent Spread of Small-Cell Lung Cancer to the Brain
(Posted: 06/20/2007, Reviewed: 08/21/2007) - Radiation therapy to the head, given to patients who had responded to chemotherapy for advanced small-cell lung cancer, reduced by about two-thirds the risk that patients' tumors would spread to the brain, according to findings presented at the 2007 ASCO meeting in Chicago.

5.  Meta-Analysis Suggests Cisplatin Superior to Carboplatin for Advanced NSCLC
(Posted: 06/19/2007) - Cisplatin is likely a better option than carboplatin for patients with advanced-stage non-small-cell lung cancer (NSCLC), according to a meta-analysis in the June 6, 2007, Journal of the National Cancer Institute.
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